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Formulation Development

Formulation Development & Consultancy

Looking to reformulate your product or optimize your consumer healthcare product formulation? Our reformulation service helps you keep your required properties while giving you the added benefits of stability and performance (e.g., optical, chemical, etc.). We will help to develop and optimize your new formulations and methods, and test them for efficacy and safety. Example areas where we’ve successfully helped clients range from dental, to pharmaceutical, to tomato ketchup!

Formulation Development

 

Improved stability

We can help you to optimize and test the stability of your products, from formulation to production, including oral care, OTC, homecare, and cosmetic products. Formulation optimization and stability during development, manufacturing, and storage is essential to, for example, drug product efficacy and safety. Whether you are looking to improve the stability of existing products or looking to incorporate it into new formulations, we can help.

Increased efficacy/loading

We can help you to increase efficacy, for example minimizing dosing burden in drugs. Many injectable and oral solid dosage forms can be restricted to very low drug concentrations per dose due to the nature of the compound. As a result, there is a risk of reduced efficacy as well as increased frequency of dosing. This can have a critical effect on patient compliance and consequently clinical outcomes. This is just one example of an area where we could help.

Enhanced aesthetics

Want to differentiate your products in a crowded market? We help manufacturers find ways to improve the appearance of their products. Optical changes to products (e.g., pharmaceutical goods) can make them more appealing to consumers, giving your product the edge against the competition. Our reformulation service provides enhanced optical properties while maintaining the functional properties of your products.

 

Replacing ingredients

The need to replace raw materials can be driven by regulatory and consumer demands, or might be required to improve the existing formulation. Altering the raw materials in a formulation, even replacing one ingredient for another, can often cause unforeseen and unwanted results. Lucideon's experts can help with this process and have the experience to introduce alternative raw materials into formulations while maintaining or even improving product performance.

Why Lucideon?

We have unrivalled experience in understanding the fundamental material science behind (re)formulation and knowing how best to achieve the outcomes you want. Common issues that we help to resolve include:

  • Instability - physical and chemical
  • Rheology and 'feel' issues
  • Optical issues – discoloration, separation

Whether you are developing a new formulation or changing or optimizing an existing one, our materials experts can help with development challenges.

Case Studies

Sun Cream
Croda: Coating Coverage & Application Optimization

Lucideon testing helps to optimize the coating process of powders

GSK Consumer Healthcare and Toothpastes

A high-resolution surface topography method was utilized to measure dentine tissue loss and surface roughness

Washing Hair
Hair Care Products

Lucideon uses surface analysis to investigate hair care products

Toothpaste and Brush
Machine Learning Optimized Product Development

A machine learning approach to predict sensory panel results for optimized oral healthcare product development

Crystallite Contamination
Drug Formulation Contamination

Analysis by time-of-flight secondary ion mass spectrometry

Toothpaste
Toothpaste Fluoride Penetration Analysis

Lucideon helps in product performance comparison