Synthesis Method of Hydroxyapatite
Due to the ageing UK population, increased dynamism of people's lives and growing life expectancy, there is an increasing clinical demand for bone replacement and repair.
The main mineral component of bone tissue is a nonstoichiometric carbonated multi-substituted apatite with calcium to phosphorus ratio (Ca:P) between 1.37 and 1.87. Synthetic hydroxyapatite is a popular bone replacement material because it has a similar crystal structure (Ca:P ratio fixed at 1.67) to native bone apatite.
This resemblance is the origin of the excellent compatibility that HA exhibits with hard tissue and its natural bioactive behaviour; enabling it to be incorporated into the body via the same processes active in the remodelling of healthy bone.
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