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Bone Cement & Substitution Development

Bone cement and its alternatives play an important role in helping orthopaedic implants integrate with the recipient's bones or helping bones heal themselves.  We validate their properties, performance, safety and cleanliness, and even improve the functionality of bone cements and other adhesives through novel materials development and process optimization.

Improving Bioactivity of Hydroxyapatite

We are actively engaged in developing novel and simplified methods for the synthesis of hydroxyapatite (HA) substituted with multi-elements (MxHA).  This new technology allows us to design the surface charge potential of the HA crystals and add intrinsic functionality and improved bioactivity to the material through the incorporation of different elements.

Applications:

  • Bone and dental replacement applications
  • Bioactive adhesives/cements
  • Drug delivery systems
  • Encapsulation
  • Fillers.

Our materials experts are currently developing:

  • New and simplified synthetic routes to manufacture HA
  • Multi-element-substituted HA with tailored charge variations via the introduction of different cations and anions into the HA lattice
  • Porous granulates containing crystallites of <100 nm
  • Nano HA crystals
  • Contract R&D and manufacturing of HA and multi-element-substituted HA.
Indication of Bioactivity by Measurement of Surface HA Growth

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Resources

  • White Paper

    Multi-Substituted Hydroxyapatites and the Role They Can Play in Advanced Bone Replacement Solutions
    pdf (848 KB)

  • White Paper

    Synthesis Method of Hydroxyapatite
    pdf (1.24 MB)

  • White Paper

    The Role of Zeta Potential in the Manufacture of Healthcare Materials
    pdf (457 KB)