Bioresorbable Stent Materials

A challenge in developing stents is that the materials which make up the stent remain in the body forever, even when they have successfully done their job.  To make a stent bioresorbable, a balance between retention of mechanical properties and degradation rates of the materials is vital.

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Lucideon has developed a series of inorganic and polymeric materials, and optimized polymer/composite processing techniques, in order to achieve:

  • Toughening of the composite vs. pure bioresorbable polymers (e.g. PLA/PGA) via addition of high loading levels of sub-micron, inorganic fillers (up to 50%)
  • Design of the correct formulation in terms of solubility of the inorganic materials and loading level to control the degradation rate of the composite
  • Incorporation of drugs into the formulation with sustained release properties but without compromising the mechanical performance.


ReBioStent

We are currently coordinating an EU FP7 project, ReBioStent, that aims to develop multifunctional biomaterials for reinforced drug-eluting stents.  It is undergoing pre-clinical studies and design optimization, but is available for licensing and development by industry partners.

» Read more about this work here

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