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  • Digital Image Correlation for Construction

    Digital Image Correlation (DIC) is a full-field image analysis method which employs high resolution digital cameras to track displacement occurring on the surface of an object. It has gained recognition for the potential that it possesses for a number of industries, not least among them the construction industry. This white paper focuses on potential applications for the construction industry drawing on examples of previous testing applications and highlighting the advantages DIC offers over conventional structural and materials testing methods.

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  • The Applications of Digital Image Correlation Technology in Healthcare

    With increased pressure from regulatory bodies demanding stringent testing throughout the design, validation and manufacturing phases of healthcare product development, test methods are becoming increasingly complex. Digital Image Correlation (DIC), offers in depth analysis, in a simple yet efficient and comprehensive manner. Using high powered digital cameras and the latest high-tech software DIC provides visual and quantitative analysis of surface strains of materials and products undergoing stress testing. Highlighting the areas of high strain informs the response of a component under various loading conditions in a non-destructive way, characterizes mechanical behavior and can verify and refine finite element analysis models.

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  • Why Quality By Design?

    The concept of Quality by Design (QbD) is not a new idea but it is only in recent years that it has been considered for all aspects of the development process for pharmaceutical products. Even with this recent growth in interest, it can often be seen an unattractive prospect, for the reasons outlined below, and is not yet considered standard for the development of drugs and pharmaceuticals.
    For those though that have taken the plunge and invested the time in developing analytical methodology for their products using QbD techniques, the advantages are being realized, reinforcing the future of QbD.
    The current success, as applied to analytical test methods, relies heavily on a significant investment in laboratory time during the early stages of a product’s life cycle. For many, spending vital time designing a method from scratch instead of it being developed from a template of a similar product seems too time consuming and counterproductive. The time spent on design does, however, offer many advantages in terms of quality control and understanding of the methodology; this, in itself, provides long-term time and cost advantages.

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  • The Advantages of Including Adverse Event Wear Testing in the Design of Orthopedic Implants

    For decades, total hip and knee replacement surgery has been successful in restoring the normal function of articulating joints. Whether the joint has been damaged through injury or as a result of arthritis, total joint replacements are some of the most common and successful orthopedic surgeries in the world.
    With approximately 160,000 total hip and knee replacements being performed in over 400 hospitals each year in the UK alone, and that number set to rise by 673 percent in the next 20 years, the design of implants, as well as the materials used in them, has become the focus of many large multinational companies. The resulting technological evolution and concurrent influx of innovative devices have increased the demand for both device and materials testing solutions.
    In this white paper we will look at why the testing of implants is so important. Traditional test methods and their limitations will be detailed and adverse event testing, including impingement testing and third body wear testing will be discussed.

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  • Abuse Deterrence for the Pharmaceutical Market

    The CDC (Centres for Disease Control and Prevention) now considers prescription drug abuse in the US an epidemic1. Abuse in these cases can be defined as the intentional misuse of pharmaceuticals to deliver a desirable physiological and psychological effect. These drugs are abused via several known routes, including chemical tampering or crushing followed by insufflation, intravenous intake or via oral abuse, using greater than prescribed doses.
    Driven by public health, governmental and regulatory bodies, such as the Food and Drug Administration (FDA), vast investment has already been made into reduction of abuse and misuse of prescription drugs. The abuse deterrence of prescriptions, particularly in the case of opioids, is a key area of concern and, as a result, a growing market has emerged.
    This paper will explore the market drivers for abuse deterrence and identify possible solutions.

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  • The Role of Controlled Release Fertilisers in Sustainable Crop Growth

    In this paper we will look at how advances are being made to create more effective, controlled fertilisers to meet the global food demand. We will explore the influences driving new fertiliser production, the need to find alternatives to conventional fertilisers and the development of inorganic controlled release fertilisers.
    Global demand for food is rising, putting strain on food production and pushing up food prices. Increased demand is coupled with a reduction in the land available for agriculture putting even more pressure on farmers to increase production.

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  • Lucideon’s Guide to Composites

    Composites are being used more and more in many different industries, thanks to the enhanced properties that are realised from the combining of materials.
    In this guide we will look at what composites are, highlighting their advantages and explaining how they work. We will also consider how to design with composites and how to test composites and components to ensure that they perform to the best of their ability.

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  • Tribology and Testing of Orthopedic Implants

    The orthopedic implant industry is in a continual state of development, witnessing an explosion of novel materials, designs, and applications. This process is, however, often laced with challenges and articulating joints can present the greatest number of these. The biocompatibility of an orthopedic implant is essential but, as an increased number of patients outlive the life expectancy of their implant; longevity is becoming a significant clinical problem. Thus, the bio-tribological performance of an implant becomes increasingly relevant.
    Bio-tribology is the study of friction, lubrication and wear as they occur in the human body and, as such, are all important factors to consider in the design of implants. Assessment of an implant covers three areas - mechanical testing, debris analysis and surface analysis. In this paper we will review the key techniques available, focusing on the value of generating a complete picture and an understanding of an orthopedic implant in terms of how the design, base material or coating behaves under friction and loading.

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  • Measuring the Chemical & Physical Properties of Human Hair Surfaces

    The surface characterisation of hair fibres can deliver important insights into the performance of hair care products and in the development of improved product formulations based on an understanding of the connection between product use and the resulting surface properties of the treated hair fibres. This paper reviews the range of relevant hair properties together with the use of topographical and chemical surface characterisation techniques for their determination. Non-contact white light interferometry and 3D scanning electron microscopy are used to investigate topographical consequences such as scale height and hair damage. These techniques provide statistically based metrology of hair surfaces either parametrically or as quantified 3D images. In addition we describe the application of chemical surface analysis techniques including X-ray Photoelectron Spectroscopy (XPS) and Secondary Ion Mass Spectrometry (SIMS) to the determination of chemical residues and natural substrates in terms of material identification, level quantification and spatial distribution. In all cases practical applications are described.

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  • Understanding Materials Choices, their Performance and Selection

    This paper sets out to affirm the value of material characterisation in product and process development activities in technology based industries, whilst sustaining the quality of manufacturing output. A selection of techniques, applications and case studies, relevant to a wide range of industry sectors are covered.
    The progress in materials development and application in almost every area of business and industry over the last 25 years has been revolutionary and is continuing to accelerate. Never before have so many material-driven innovations enabled the global spread of technology and improvements in capability, from communications to aerospace and healthcare, to agriculture and automotive.
    Central to this progress has been the improvement in our ability to define materials in terms of their composition, structure and performance evaluation. Together with material design and processing, these have been the bedrock of successful new material applications. Lucideon has participated in this era of materials proliferation for over 50 years. In this review, we will highlight a few of the areas where the characterisation of materials has been crucial to the successful outcomes of client projects.

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